Consensus on the use of oral isotretinoin in dermatology - Brazilian Society of Dermatology,
Abstract Background: Isotretinoin is a synthetic retinoid, derived from vitamin A, with multiple mechanisms of action and highly effective in the treatment of acne, despite common adverse events, manageable and dose-dependent.Dose-independent teratogenicity is the most serious.Therefore, off-label prescriptions require strict criteria.Objective: To